The first symptom of Bowen’s disease is a red looking patch with an uneven boundary. The patch may appear on an area of the skin, especially the sun exposed area. Few of the other symptoms include: Ulcer. Bleeding lump.DFDAFF
The main causes of this disease include: Exposure to UV radiations. Formation of mutant clone gene, p53. Uncontrolled growth of skin cells.
The disease can be suspected by appearance of patch on the skin. To rule out the occurrence, a small sample of skin for biopsy purpose is taken. The sample is examined closely under the microscope for the presence of squamous cells.
Cryotherapy The affected area is freezed with the help of nitrogen spray. Though the procedure is painful, yet effective as the skin scabs and falls off by itself after a few days. Chemotherapy The Imiquimod ointment like 5-fluorouracil is applied onto the affected area for a due course of time. The ointment causes the skin to inflammate and become red. Gradually, the area becomes better with time. Curettage and cautery Under the effect of local anesthesia, the affected skin is numbed and scraped or removed. Heat or electricity is used to stop bleeding and left to heal over time. Antibiotics are prescribed to keep away infections. PDT (Photodynamic Therapy) With the help of laser, cells of the affected area are burnt or killed. The procedure is completed with the help of a light-sensitive cream. The entire course lasts for about 20-45 minutes, and the number of sittings may vary depending on the requirement. Surgery This forms the last option of treatment in any case. It involves removing the affected skin under local anesthesia effect, and then stitching to seal the wound.
In order to prevent the occurrence of this disease, one should take care of the following: Using a sunscreen which has at least SPF 15. Staying in the shade as much as possible. Covering up the skin while exposure to sun.
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